GMDS anticorps

N° du produit ABIN7228678

Cet anticorps Lapin Polyclonal détecte spécifiquement GMDS dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour GMDS anticorps (ABIN7228678)

Antigène: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GMDS est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GMDS anticorps

Fonction: Rabbit Anti-GMDS Polyclonal Antibody

Specificité: The antibody detects endogenous levels of GMDS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human GMDS protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GMDS

Antigène: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Autre désignation: GMDS

Sujet: GDP-mannose 4,6 dehydratase , GDP-D-mannose dehydratase, GMDGDP-mannose 4,6-dehydratase catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020). GMDS (GDP-Mannose 4,6-Dehydratase) is a Protein Coding gene. Diseases associated with GMDS include Congenital Disorder Of Glycosylation, Type Iic and Partial Fetal Alcohol Syndrome. Among its related pathways are Amino sugar and nucleotide sugar metabolism and Transport to the Golgi and subsequent modification.

Poids moléculaire: 40kD

ID gène: 2762

UniProt: O60547