GTF3A anticorps (Internal Region)

N° du produit ABIN7221396

Cet anticorps Lapin Polyclonal détecte spécifiquement GTF3A dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GTF3A anticorps (Internal Region) (ABIN7221396)

Antigène: GTF3A (General Transcription Factor IIIA (GTF3A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF3A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GTF3A anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-TFIIIA Polyclonal Antibody

Specificité: TFIIIA Polyclonal Antibody detects endogenous levels of TFIIIA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human TFIIIA

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GTF3A

Antigène: GTF3A (General Transcription Factor IIIA (GTF3A))

Autre désignation: TFIIIA

Sujet: GTF3A, Transcription factor IIIA, TFIIIAThe product of GTF3A is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.

Poids moléculaire: 41kD

ID gène: 2971

UniProt: Q92664