Glutamate Receptor 1 anticorps (pSer863)

N° du produit ABIN7221294

Cet anticorps anti-Glutamate Receptor 1 Polyclonal Lapin (ABIN7221294) détecte spécifiquement Glutamate Receptor 1 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Glutamate Receptor 1 anticorps (pSer863) (ABIN7221294)

Antigène: Glutamate Receptor 1 (GLUR1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Glutamate Receptor 1 anticorps

Épitope: pSer863

Fonction: Rabbit Anti-GluR-1 (phospho Ser863) Polyclonal Antibody

Specificité: Phospho-GluR-1 (S863) Polyclonal Antibody detects endogenous levels of GluR-1 protein only when phosphorylated at S863.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human GluR-1 Phospho-Ser863

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GluR-1

Sujet: GRIA1, GLUH1, GLUR1, Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 102kD

ID gène: 2890

UniProt: P42261

Pathways: Signalisation PI3K-Akt