GRM2 anticorps (AA 210-290)

N° du produit ABIN7221364

L’anticorps Lapin Polyclonal anti-GRM2 a été validé pour ELISA, IF et IHC (p). Il convient pour détecter GRM2 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour GRM2 anticorps (AA 210-290) (ABIN7221364)

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GRM2 anticorps

Épitope: AA 210-290

Fonction: mGluR2 Polyclonal Antibody

Specificité: MGluR2 Polyclonal Antibody detects endogenous levels of mGluR2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human mGluR2 at AA range: 210-290

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur GRM2

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Autre désignation: mGluR2

Sujet: Rabbit Anti-mGluR2 Polyclonal Antibody,GRM2, GPRC1B, MGLUR2, Metabotropic glutamate receptor 2, mGluR2,L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for GRM2.,Metabotropic glutamate receptor 2

ID gène: 2912

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport