Metabotropic Glutamate Receptor 4 anticorps (AA 820-900)

N° du produit ABIN7215752

L’anticorps anti-Metabotropic Glutamate Receptor 4 Polyclonal produit chez le Lapin a été validé pour WB, ELISA et IHC (p). Il convient pour la détection de Metabotropic Glutamate Receptor 4 dans des échantillons provenant de Humain, Rat et Souris. }

Aperçu rapide pour Metabotropic Glutamate Receptor 4 anticorps (AA 820-900) (ABIN7215752)

Antigène: Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Metabotropic Glutamate Receptor 4 anticorps

Épitope: AA 820-900

Fonction: mGluR-4 Polyclonal Antibody

Specificité: MGluR-4 Polyclonal Antibody detects endogenous levels of mGluR-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human mGluR-4 at AA range: 820-900

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Metabotropic Glutamate Receptor 4

Antigène: Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))

Autre désignation: mGluR-4

Sujet: Rabbit Anti-mGluR-4 Polyclonal Antibody,GRM4, GPRC1D, MGLUR4, Metabotropic glutamate receptor 4, mGluR4,L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for GRM4.,Metabotropic glutamate receptor 4

Poids moléculaire: observerd band 100kDa

ID gène: 2914

UniProt: Q14833