GLRB anticorps (AA 180-260)

N° du produit ABIN7221158

Cet anticorps anti-GLRB Polyclonal Lapin (ABIN7221158) détecte spécifiquement GLRB dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GLRB anticorps (AA 180-260) (ABIN7221158)

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLRB est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GLRB anticorps

Épitope: AA 180-260

Fonction: Rabbit Anti-GlyRβ Polyclonal Antibody

Specificité: GlyRβ Polyclonal Antibody detects endogenous levels of GlyRβ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human GlyRbeta at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GLRB

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Autre désignation: GlyRbeta

Sujet: GLRB, Glycine receptor subunit beta, Glycine receptor 58 kDa subunitGLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 56kD

ID gène: 2743

UniProt: P48167