GP5 anticorps (Internal Region)

N° du produit ABIN7218678

L’anticorps anti-GP5 Polyclonal Lapin est utilisé pour la détection de GP5 dans des échantillons de Souris, Humain et Rat. Il a été validé pour WB, FACS, IHC, ELISA et IF.

Aperçu rapide pour GP5 anticorps (Internal Region) (ABIN7218678)

Antigène: GP5 (Glycoprotein V (Platelet) (GP5))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GP5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-GP5 anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-CD42d Polyclonal Antibody

Specificité: CD42d Polyclonal Antibody detects endogenous levels of CD42d protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CD42d

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GP5

Antigène: GP5 (Glycoprotein V (Platelet) (GP5))

Autre désignation: CD42d

Sujet: GP5, Platelet glycoprotein V, GPV, Glycoprotein 5, CD42dHuman platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF, MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA, MIM 606672) and a beta chain (GP1BB, MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9, MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al. 1998 [PubMed: 9616133]).

Poids moléculaire: 62kD

ID gène: 2814

UniProt: P40197