GNRHR anticorps (AA 10-90)

N° du produit ABIN7221168

L’anticorps anti-GNRHR Polyclonal Lapin est utilisé pour la détection de GNRHR dans des échantillons de Humain et Souris. Il a été validé pour WB, IF et ELISA.

Aperçu rapide pour GNRHR anticorps (AA 10-90) (ABIN7221168)

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNRHR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Détail du produit anti-GNRHR anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-GnRH-R Polyclonal Antibody

Specificité: GnRH-R Polyclonal Antibody detects endogenous levels of GnRH-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human GnRH-R at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GNRHR

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Autre désignation: GnRH-R

Sujet: GNRHR, GRHR, Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-RGNRHR encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Poids moléculaire: 37kD

ID gène: 2798

UniProt: P30968