GZMH anticorps (AA 30-110)
Aperçu rapide pour GZMH anticorps (AA 30-110) (ABIN7221430)
Antigène
Voir toutes GZMH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-110
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Fonction
- Rabbit Anti-Granzyme H Polyclonal Antibody
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Specificité
- Granzyme H Polyclonal Antibody detects endogenous levels of Granzyme H protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human Granzyme H at AA range: 30-110
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
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Autre désignation
- Granzyme H
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Sujet
- GZMH, CGL2, CTSGL2, Granzyme H, CCP-X, Cathepsin G-like 2, CTSGL2, Cytotoxic T-lymphocyte proteinase, Cytotoxic serine protease C, CSP-CGZMH encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. Granzyme H is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. GZMH is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
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Poids moléculaire
- 23kD
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ID gène
- 2999
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UniProt
- P20718
Antigène
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