GREM2 anticorps (AA 71-120)

N° du produit ABIN7228780

L’anticorps anti-GREM2 Polyclonal Lapin est utilisé pour la détection de GREM2 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour GREM2 anticorps (AA 71-120) (ABIN7228780)

Antigène: GREM2 (Gremlin 2 (GREM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GREM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-GREM2 anticorps

Épitope: AA 71-120

Fonction: Rabbit Anti-Gremlin-2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of Gremlin-2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human Gremlin-2 protein at AA range: 71-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:500-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GREM2

Antigène: GREM2 (Gremlin 2 (GREM2))

Autre désignation: Gremlin-2

Sujet: Gremlin-2, Cysteine knot superfamily 1, BMP antagonist 2, DAN domain family member 3, Protein related to DAN and cerberusGremlin-2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which Gremlin-2 belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, Gremlin-2 may play a role in regulating organogenesis, body patterning, and tissue differentiation.

Poids moléculaire: 19kD

ID gène: 64388

UniProt: Q9H772