GDF2 anticorps (AA 371-420)

N° du produit ABIN7227494

Cet anticorps Lapin Polyclonal détecte spécifiquement GDF2 dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour GDF2 anticorps (AA 371-420) (ABIN7227494)

Antigène: GDF2 (Growth Differentiation Factor 2 (GDF2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-GDF2 anticorps

Épitope: AA 371-420

Fonction: Rabbit Anti-BMP-9 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of BMP-9

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human BMP-9 protein at AA range: 371-420

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GDF2

Antigène: GDF2 (Growth Differentiation Factor 2 (GDF2))

Autre désignation: BMP-9

Sujet: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9GDF2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in GDF2 are associated with hereditary hemorrhagic telangiectasia.

ID gène: 2658

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis