GBP5 anticorps (Internal Region)
Aperçu rapide pour GBP5 anticorps (Internal Region) (ABIN7219352)
Antigène
Voir toutes GBP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- Rabbit Anti-GBP5 Polyclonal Antibody
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Specificité
- GBP5 Polyclonal Antibody detects endogenous levels of GBP5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human GBP5
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- GBP5 (Guanylate Binding Protein 5 (GBP5))
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Autre désignation
- GBP5
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Sujet
- GBP5, Guanylate-binding protein 5, GBP-TA antigen, GTP-binding protein 5, GBP-5, Guanine nucleotide-binding protein 5GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include chronic active epstein-barr virus infection. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP7. s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847).
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Poids moléculaire
- 66kD
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ID gène
- 115362
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UniProt
- Q96PP8
Antigène
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