H2AFZ anticorps (AA 1-30)

N° du produit ABIN7227046

Cet anticorps anti-H2AFZ Polyclonal Lapin (ABIN7227046) détecte spécifiquement H2AFZ dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour H2AFZ anticorps (AA 1-30) (ABIN7227046)

Antigène: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H2AFZ est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-H2AFZ anticorps

Épitope: AA 1-30

Fonction: Rabbit Anti-Histone H2A.Z Polyclonal Antibody

Specificité: The antibody detects endogenous Histone H2A.Z.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic peptide from human protein at AA range: 1-30

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur H2AFZ

Antigène: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Autre désignation: Histone H2A.Z

Sujet: Histone H2A.Z, H2A/zHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFZ (H2A histone family member Z) encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Poids moléculaire: 20kD

ID gène: 3015

UniProt: P0C0S5

Pathways: Telomere Maintenance