HAND2 anticorps

N° du produit ABIN7228838

L’anticorps Lapin Polyclonal anti-HAND2 a été validé pour WB et ELISA. Il convient pour détecter HAND2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HAND2 anticorps (ABIN7228838)

Antigène: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAND2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HAND2 anticorps

Fonction: HAND2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of HAND2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human HAND2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur HAND2

Antigène: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Autre désignation: HAND2

Sujet: Rabbit Anti-HAND2 Polyclonal Antibody,Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND,Heart And Neural Crest Derivatives Expressed 2 encoded by HAND2 belongs to the basic helix-loop-helix family of transcription factors. HAND2 product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. HAND2 (Heart And Neural Crest Derivatives Expressed 2) is a Protein Coding gene. Diseases associated with HAND2 include Saethre-Chotzen Syndrome and Split Hand-Foot Malformation. Among its related pathways are NFAT and Cardiac Hypertrophy and Heart Development.,HAND2

Poids moléculaire: observerd band 23kDa

ID gène: 9464

UniProt: P61296

Pathways: Tube Formation, Feeding Behaviour