ATRX anticorps (AA 80-160)

N° du produit ABIN7223298

L’anticorps Lapin Polyclonal anti-ATRX a été validé pour ELISA et IF. Il convient pour détecter ATRX dans des échantillons de Humain et Souris.

Aperçu rapide pour ATRX anticorps (AA 80-160) (ABIN7223298)

Antigène: ATRX (helicase 2, X-linked (ATRX))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATRX est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-ATRX anticorps

Épitope: AA 80-160

Fonction: ATRX Polyclonal Antibody

Specificité: ATRX Polyclonal Antibody detects endogenous levels of ATRX protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human ATRX at AA range: 80-160

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ATRX

Antigène: ATRX (helicase 2, X-linked (ATRX))

Autre désignation: ATRX

Sujet: Rabbit Anti-ATRX Polyclonal Antibody,ATRX, RAD54L, XH2, Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX,The protein encoded by ATRX (ATRX, chromatin remodeler) contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in ATRX are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.,Transcriptional regulator ATRX

ID gène: 546

UniProt: P46100