HDAC6 anticorps (pSer22)

N° du produit ABIN7218848

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC6 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour HDAC6 anticorps (pSer22) (ABIN7218848)

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-HDAC6 anticorps

Épitope: pSer22

Fonction: Rabbit Anti-HDAC6 (phospho Ser22) Polyclonal Antibody

Specificité: Phospho-HDAC6 (S22) Polyclonal Antibody detects endogenous levels of HDAC6 protein only when phosphorylated at S22.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human HDAC6 Phospho-Ser22

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6

Sujet: HDAC6, KIAA0901, JM21, Histone deacetylase 6, HD6Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Poids moléculaire: 131kD

ID gène: 10013

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling