Histone H2A anticorps (pThr121)
Aperçu rapide pour Histone H2A anticorps (pThr121) (ABIN7225254)
Antigène
Voir toutes Histone H2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr121
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Fonction
- Rabbit Anti-Histone H2A (phospho Thr121) Polyclonal Antibody
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Specificité
- Phospho-Histone H2A (T121) Polyclonal Antibody detects endogenous levels of Histone H2A protein only when phosphorylated at T121.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human Histone H2A Phospho-Thr121
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Histone H2A
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Sujet
- HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN, Histone H2A type 1, H2A.1, Histone H2A/p, HIST1H2AB, H2AFM, HIST1H2AE, H2AFA, Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, HISHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H2AI (histone cluster 1 H2A family member i) is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from HIST1H2AI lack polyA tails but instead contain a palindromic termination element. HIST1H2AI is found in the small histone gene cluster on chromosome 6p22-p21.3.
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ID gène
- 8329, 8332, 8336
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UniProt
- P0C0S8, P04908, P20671, Q96KK5, Q6FI13, Q7L7L0
Antigène
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