Histone H2B anticorps (H2BK21ac)

N° du produit ABIN7228910

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone H2B dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Histone H2B anticorps (H2BK21ac) (ABIN7228910)

Antigène: Histone H2B

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Histone H2B anticorps

Épitope: H2BK21ac

Fonction: Rabbit Anti-Histone H2B (Acetyl Lys21) Polyclonal Antibody

Specificité: The antibody detects endogenous levels of Histone H2B when Acetyl occurs at Lys21

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human Histone H2B (Acetyl Lys21) protein at AA range: 21

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Histone H2B

Antigène: Histone H2B

Sujet: Histone H2B type 1-A, HIST1H2BA, Histone H2B, testis, TSH2B.1, hTSH2B1, Testis-specific histone H2BHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H2BA is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from HIST1H2BA contain a palindromic termination element. HIST1H2BA (Histone Cluster 1 H2B Family Member A) is a Protein Coding gene. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and DNA Double Strand Break Response.

Poids moléculaire: 15kD

ID gène: 255626

UniProt: Q96A08, P33778, P62807