Homeobox Protein 5 (LOC101458951) anticorps
Aperçu rapide pour Homeobox Protein 5 (LOC101458951) anticorps (ABIN7231354)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SHAN3 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SHAN3 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human SHAN3 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Homeobox Protein 5 (LOC101458951)
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Autre désignation
- SHAN3
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Sujet
- Rabbit Anti-SHAN3 Polyclonal Antibody,SH3 and multiple ankyrin repeat domains protein 3, Shank3, Proline-rich synapse-associated protein 2, ProSAP2,SHANK3 is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in SHANK3 are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in SHANK3 also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for SHANK3 but they have not yet been experimentally verified.,SHAN3
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Poids moléculaire
- observerd band 191kDa
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ID gène
- 85358
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UniProt
- Q9BYB0
Antigène
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