HCN4 anticorps (AA 600-680)

N° du produit ABIN7228872

L’anticorps anti-HCN4 Polyclonal Lapin est utilisé pour la détection de HCN4 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour HCN4 anticorps (AA 600-680) (ABIN7228872)

Antigène: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCN4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HCN4 anticorps

Épitope: AA 600-680

Fonction: Rabbit Anti-HCN4 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of HCN4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human HCN4 protein at AA range: 600-680

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HCN4

Antigène: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Autre désignation: HCN4

Sujet: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4HCN4 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4) encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in HCN4 have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.

Poids moléculaire: 132kD

ID gène: 10021

UniProt: Q9Y3Q4