IRGM anticorps (AA 101-150)
Aperçu rapide pour IRGM anticorps (AA 101-150) (ABIN7229186)
Antigène
Voir toutes IRGM AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-150
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Fonction
- Rabbit Anti-IRGM Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of IRGM protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human IRGM protein at AA range: 101-150
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- IRGM (Immunity-Related GTPase Family, M (IRGM))
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Autre désignation
- IRGM
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Sujet
- Immunity-related GTPase family M protein, Immunity-related GTPase family M protein 1, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of IRGM are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Poids moléculaire
- 19kD
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ID gène
- 345611
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UniProt
- A1A4Y4
Antigène
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