ITFG2 anticorps (AA 40-120)

N° du produit ABIN7229200

L’anticorps Lapin Polyclonal anti-ITFG2 a été validé pour WB et ELISA. Il convient pour détecter ITFG2 dans des échantillons de Humain et Souris.

Aperçu rapide pour ITFG2 anticorps (AA 40-120) (ABIN7229200)

Antigène: ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITFG2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ITFG2 anticorps

Épitope: AA 40-120

Fonction: ITFG2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ITFG2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human ITFG2 protein at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ITFG2

Antigène: ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

Autre désignation: ITFG2

Sujet: Rabbit Anti-ITFG2 Polyclonal Antibody,KICSTOR complex protein ITFG2, Integrin-alpha FG-GAP repeat-containing protein 2,ITFG2 (Integrin Alpha FG-GAP Repeat Containing 2) is a Protein Coding gene. Diseases associated with ITFG2 include Distal Arthrogryposis. As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.,ITFG2

Poids moléculaire: observerd band 49kDa

ID gène: 55846

UniProt: Q969R8