ITFG2 anticorps (AA 40-120)

N° du produit ABIN7229200

L’anticorps anti-ITFG2 Polyclonal Lapin est utilisé pour la détection de ITFG2 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour ITFG2 anticorps (AA 40-120) (ABIN7229200)

Antigène: ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITFG2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ITFG2 anticorps

Épitope: AA 40-120

Fonction: Rabbit Anti-ITFG2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ITFG2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ITFG2 protein at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ITFG2

Antigène: ITFG2 (Integrin alpha FG-GAP Repeat Containing 2 (ITFG2))

Autre désignation: ITFG2

Sujet: KICSTOR complex protein ITFG2, Integrin-alpha FG-GAP repeat-containing protein 2ITFG2 (Integrin Alpha FG-GAP Repeat Containing 2) is a Protein Coding gene. Diseases associated with ITFG2 include Distal Arthrogryposis. As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.

Poids moléculaire: 49kD

ID gène: 55846

UniProt: Q969R8