Integrin AlphaV HC (AA 810-890), (Cleaved-Lys889) anticorps

N° du produit ABIN7212526

Cet anticorps anti-Integrin AlphaV HC Polyclonal Lapin (ABIN7212526) détecte spécifiquement Integrin AlphaV HC dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Integrin AlphaV HC (AA 810-890), (Cleaved-Lys889) anticorps (ABIN7212526)

Antigène: Integrin AlphaV HC

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Détail du produit

Épitope: AA 810-890, Cleaved-Lys889

Fonction: Rabbit Anti-Cleaved-Integrin αV HC (K889) Polyclonal Antibody

Specificité: Cleaved-Integrin αV HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin αV HC protein resulting from cleavage adjacent to K889.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Integrin alphaV HC at AA range: 810-890

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Integrin AlphaV HC

Sujet: ITGAV, MSK8, VNRA, Integrin alpha-V, Vitronectin receptor subunit alpha, CD antigen CD51The product of ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Poids moléculaire: 95kD

ID gène: 3685

UniProt: P06756