ITGB1BP2 anticorps (AA 10-90)
Aperçu rapide pour ITGB1BP2 anticorps (AA 10-90) (ABIN7229198)
Antigène
Voir toutes ITGB1BP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 10-90
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Fonction
- ITBP2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of ITBP2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human ITBP2 protein at AA range: 10-90
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ITGB1BP2 (Integrin beta 1 Binding Protein (Melusin) 2 (ITGB1BP2))
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Autre désignation
- ITBP2
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Sujet
- Rabbit Anti-ITBP2 Polyclonal Antibody,Integrin beta-1-binding protein 2, Melusin,ITGB1BP2 encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of ITGB1BP2 indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains.,ITBP2
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Poids moléculaire
- observerd band 38kDa
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ID gène
- 26548
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UniProt
- Q9UKP3
Antigène
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