Integrin beta 7 anticorps (AA 671-720)
Aperçu rapide pour Integrin beta 7 anticorps (AA 671-720) (ABIN7229170)
Antigène
Voir toutes Integrin beta 7 (ITGB7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 671-720
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Fonction
- Integrin β7 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of Integrin β7
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human Integrin beta7 protein at AA range: 671-720
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Integrin beta 7 (ITGB7)
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Autre désignation
- Integrin beta7
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Sujet
- Rabbit Anti-Integrin β7 Polyclonal Antibody,Integrin beta-7, Gut homing receptor beta subunit,ITGB7 encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,Integrin β7
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Poids moléculaire
- observerd band 130kDa
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ID gène
- 3695
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UniProt
- P26010
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Pathways
- Integrin Complex
Antigène
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