Integrin beta 7 anticorps (AA 671-720)

N° du produit ABIN7229170

Cet anticorps anti-Integrin beta 7 Polyclonal Lapin (ABIN7229170) détecte spécifiquement Integrin beta 7 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Integrin beta 7 anticorps (AA 671-720) (ABIN7229170)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Integrin beta 7 anticorps

Épitope: AA 671-720

Fonction: Rabbit Anti-Integrin β7 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of Integrin β7

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human Integrin beta7 protein at AA range: 671-720

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: Integrin beta7

Sujet: Integrin beta-7, Gut homing receptor beta subunitITGB7 encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Poids moléculaire: 130kD

ID gène: 3695

UniProt: P26010

Pathways: Integrin Complex