ITLN1/Omentin anticorps (AA 110-190)

N° du produit ABIN7229202

Cet anticorps Lapin Polyclonal détecte spécifiquement ITLN1/Omentin dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour ITLN1/Omentin anticorps (AA 110-190) (ABIN7229202)

Antigène: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITLN1/Omentin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ITLN1/Omentin anticorps

Épitope: AA 110-190

Fonction: Rabbit Anti-ITLN1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ITLN1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ITLN1 protein at AA range: 110-190

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ITLN1/Omentin

Antigène: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Autre désignation: ITLN1

Sujet: Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, OmentinITLN1 (Intelectin 1) is a Protein Coding gene. Diseases associated with ITLN1 include Obesity and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is ITLN2. Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed: 11313366, PubMed: 26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed: 26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K. neumoniae, S. neumoniae, Y. estis, P. irabilis and P. ulgaris (PubMed: 26148048). Does not bind human glycans (PubMed: 26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed: 16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed: 16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed: 11747454, PubMed: 23921499).

Poids moléculaire: 34kD

ID gène: 55600

UniProt: Q8WWA0