IFIT2 anticorps (AA 200-280)

N° du produit ABIN7229032

L’anticorps anti-IFIT2 Polyclonal Lapin est utilisé pour la détection de IFIT2 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour IFIT2 anticorps (AA 200-280) (ABIN7229032)

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IFIT2 anticorps

Épitope: AA 200-280

Fonction: Rabbit Anti-IFIT2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of IFIT2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human IFIT2 protein at AA range: 200-280

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IFIT2

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Autre désignation: IFIT2

Sujet: Interferon-induced protein with tetratricopeptide repeats 2, IFIT-2, ISG-54 K, Interferon-induced 54 kDa protein, IFI-54K, P54IFIT2 (Interferon Induced Protein With Tetratricopeptide Repeats 2) is a Protein Coding gene. Among its related pathways are Type II interferon signaling (IFNG) and Interferon gamma signaling. IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2-O-methylation of the 5 cap. The ribose 2-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2-O-methylase for their mRNAs or by stealing host cap containing the 2-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5 triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Poids moléculaire: 51kD

ID gène: 3433

UniProt: P09913