ILF2 anticorps
Aperçu rapide pour ILF2 anticorps (ABIN7229124)
Antigène
Voir toutes ILF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ILF2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of ILF2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human ILF2 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))
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Autre désignation
- ILF2
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Sujet
- Rabbit Anti-ILF2 Polyclonal Antibody,Interleukin enhancer-binding factor 2, Nuclear factor of activated T-cells 45 kDa,The protein encoded by ILF2 gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.,ILF2
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Poids moléculaire
- observerd band 42kDa
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ID gène
- 3608
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UniProt
- Q12905
Antigène
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