ILF2 anticorps

N° du produit ABIN7229124

Cet anticorps Lapin Polyclonal détecte spécifiquement ILF2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ILF2 anticorps (ABIN7229124)

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILF2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ILF2 anticorps

Fonction: Rabbit Anti-ILF2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ILF2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ILF2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ILF2

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Autre désignation: ILF2

Sujet: Interleukin enhancer-binding factor 2, Nuclear factor of activated T-cells 45 kDaThe protein encoded by ILF2 gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

Poids moléculaire: 42kD

ID gène: 3608

UniProt: Q12905