IQGAP1 anticorps (AA 220-300)

N° du produit ABIN7215470

L’anticorps anti-IQGAP1 Polyclonal Lapin est utilisé pour la détection de IQGAP1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour IQGAP1 anticorps (AA 220-300) (ABIN7215470)

Antigène: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IQGAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IQGAP1 anticorps

Épitope: AA 220-300

Fonction: Rabbit Anti-IQGAP1 Polyclonal Antibody

Specificité: IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human IQGAP1 at AA range: 220-300

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IQGAP1

Antigène: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Autre désignation: IQGAP1

Sujet: IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195IQGAP1 encodes a member of the IQGAP family. Ras GTPase-activating-like protein IQGAP1 contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Poids moléculaire: 190kD

ID gène: 8826

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2