JTB anticorps (AA 20-100)

N° du produit ABIN7219176

L’anticorps anti-JTB Polyclonal Lapin est utilisé pour la détection de JTB dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour JTB anticorps (AA 20-100) (ABIN7219176)

Antigène: JTB (Jumping Translocation Breakpoint (JTB))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JTB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-JTB anticorps

Épitope: AA 20-100

Fonction: Rabbit Anti-JTB Polyclonal Antibody

Specificité: JTB Polyclonal Antibody detects endogenous levels of JTB protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human JTB at AA range: 20-100

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur JTB

Antigène: JTB (Jumping Translocation Breakpoint (JTB))

Autre désignation: JTB

Sujet: JTB, HSPC222, Protein JTB, Jumping translocation breakpoint protein, Prostate androgen-regulated protein, PAR proteinRequired for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

Poids moléculaire: 17kD

ID gène: 10899

UniProt: O76095