JunB anticorps
Aperçu rapide pour JunB anticorps (ABIN7221960)
Antigène
Voir toutes JunB (JUNB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Jun B Polyclonal Antibody
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Specificité
- Jun B Polyclonal Antibody detects endogenous levels of Jun B protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human Jun B around the non-phosphorylation site of S259
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IP (2-5 μg/mg lysate), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- JunB (JUNB) (Jun B Proto-Oncogene (JUNB))
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Autre désignation
- Jun B
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Sujet
- Rabbit Anti-Jun B Polyclonal Antibody,JUNB, Transcription factor jun-B,JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML).,Transcription factor jun-B
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Poids moléculaire
- observerd band 36kDa
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ID gène
- 3726
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UniProt
- P17275
Antigène
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