JunB anticorps

N° du produit ABIN7221960

L’anticorps anti-JunB Polyclonal Lapin est utilisé pour la détection de JunB dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, IP, ELISA et IF.

Aperçu rapide pour JunB anticorps (ABIN7221960)

Antigène: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JunB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Détail du produit anti-JunB anticorps

Fonction: Rabbit Anti-Jun B Polyclonal Antibody

Specificité: Jun B Polyclonal Antibody detects endogenous levels of Jun B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Jun B around the non-phosphorylation site of S259

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IP 2-5 μg:mg lysate,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur JunB

Antigène: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Autre désignation: Jun B

Sujet: JUNB, Transcription factor jun-BJunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML).

Poids moléculaire: 36kD

ID gène: 3726

UniProt: P17275