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KRT8 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement KRT8 dans WB, IF, ELISA et IHC (p). Il présente une réactivité envers Humain, Souris et Singe.
N° du produit ABIN7214498

Aperçu rapide pour KRT8 anticorps (ABIN7214498)

Antigène

Voir toutes KRT8 Anticorps
KRT8 (Keratin 8 (KRT8))

Reactivité

  • 314
  • 89
  • 87
  • 67
  • 66
  • 64
  • 63
  • 16
  • 13
  • 10
  • 8
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Singe

Hôte

  • 167
  • 159
  • 3
Lapin

Clonalité

  • 187
  • 139
  • 1
Polyclonal

Conjugué

  • 171
  • 26
  • 17
  • 8
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Cet anticorp KRT8 est non-conjugé

Application

  • 232
  • 161
  • 129
  • 102
  • 72
  • 52
  • 46
  • 41
  • 41
  • 39
  • 35
  • 30
  • 23
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Fonction

    Cytokeratin 8 Polyclonal Antibody

    Specificité

    Cytokeratin 8 Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogène

    Synthesized peptide derived from human Cytokeratin 8 around the non-phosphorylation site of S73

    Isotype

    IgG
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

    Commentaires

    Primary Antibody

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Antigène

    KRT8 (Keratin 8 (KRT8))

    Autre désignation

    Cytokeratin 8

    Sujet

    Rabbit Anti-Cytokeratin 8 Polyclonal Antibody,KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8,KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.,Keratin type II cytoskeletal 8

    Poids moléculaire

    observerd band 52kDa

    ID gène

    3856

    UniProt

    P05787
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