KRT8 anticorps
Aperçu rapide pour KRT8 anticorps (ABIN7214498)
Antigène
Voir toutes KRT8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- Cytokeratin 8 Polyclonal Antibody
-
Specificité
- Cytokeratin 8 Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogène
- Synthesized peptide derived from human Cytokeratin 8 around the non-phosphorylation site of S73
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- KRT8 (Keratin 8 (KRT8))
-
Autre désignation
- Cytokeratin 8
-
Sujet
- Rabbit Anti-Cytokeratin 8 Polyclonal Antibody,KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8,KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.,Keratin type II cytoskeletal 8
-
Poids moléculaire
- observerd band 52kDa
-
ID gène
- 3856
-
UniProt
- P05787
Antigène
-