KRT8 anticorps
Aperçu rapide pour KRT8 anticorps (ABIN7229280)
Antigène
Voir toutes KRT8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- Keratin 8 Polyclonal Antibody
-
Specificité
- This antibody detects endogenous levels of Keratin 8.
-
Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
Immunogène
- Synthesized peptide derived from part region of human Keratin 8 protein
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- KRT8 (Keratin 8 (KRT8))
-
Autre désignation
- Keratin 8
-
Sujet
- Rabbit Anti-Keratin 8 Polyclonal Antibody,Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8,KRT8 (Keratin 8) is a Protein Coding gene. Diseases associated with KRT8 include Cirrhosis, Cryptogenic and Hidrocystoma. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization. KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.,Keratin 8
-
Poids moléculaire
- observerd band 53kDa
-
ID gène
- 3856
-
UniProt
- P05787
Antigène
-