pan Keratin anticorps (AA 150-220)

N° du produit ABIN7229282

Cet anticorps Lapin Polyclonal détecte spécifiquement pan Keratin dans IHC, WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour pan Keratin anticorps (AA 150-220) (ABIN7229282)

Antigène: pan Keratin (panKRT)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp pan Keratin est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-pan Keratin anticorps

Épitope: AA 150-220

Fonction: Rabbit Anti-Keratin-pan Polyclonal Antibody

Specificité: The antibody detects endogenous levels of Keratin-pan

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human Keratin-pan protein at AA range: 150-220

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur pan Keratin

Antigène: pan Keratin (panKRT)

Autre désignation: Keratin-pan

Sujet: Keratin, type II cytoskeletal 2 epidermal, KRT2, Cytokeratin-2e, CK-2e, Epithelial keratin-2e, Keratin-2 epidermis, Keratin-2e, K2e, Type-II keratin Kb2, KRT2, KRT2A, KRT2EThe protein encoded by KRT2 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in KRT2 have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. KRT2 (Keratin 2) is a Protein Coding gene. Diseases associated with KRT2 include Ichthyosis Bullosa Of Siemens and Exfoliative Ichthyosis. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Keratinization.

Poids moléculaire: 70kD

ID gène: 3849

UniProt: P35908, Q01546, P12035, P13647, P02538, P04259, P48668, Q3SY84, Q14CN4, Q86Y46, Q7RTS7, O95678, Q5XKE5, P08729, P05787, Q9NSB2