Kininogen-1 Heavy Chain (AA 300-380), (Cleaved-Lys380) anticorps

N° du produit ABIN7222046

Cet anticorps anti-Kininogen-1 Heavy Chain est un anticorps Polyclonal produit chez le Lapin, détectant Kininogen-1 Heavy Chain dans ELISA et WB. Convient pour Humain.

Aperçu rapide pour Kininogen-1 Heavy Chain (AA 300-380), (Cleaved-Lys380) anticorps (ABIN7222046)

Antigène: Kininogen-1 Heavy Chain

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Détail du produit

Épitope: AA 300-380, Cleaved-Lys380

Fonction: Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody

Specificité: Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody detects endogenous levels of fragment of activated Kininogen-1 HC protein resulting from cleavage adjacent to K380.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Kininogen-1 HC at AA range: 300-380

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détail du antigène

Antigène: Kininogen-1 Heavy Chain

Autre désignation: Kininogen-1 HC

Sujet: Rabbit Anti-Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody,KNG1, BDK, KNG, Kininogen-1, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Williams-Fitzgerald-Flaujeac factor,KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.,Kininogen-1

Poids moléculaire: observerd band 41kDa

ID gène: 3827

UniProt: P01042