L1CAM anticorps (pSer1181)

N° du produit ABIN7222078

Cet anticorps anti-L1CAM Polyclonal Lapin (ABIN7222078) détecte spécifiquement L1CAM dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour L1CAM anticorps (pSer1181) (ABIN7222078)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-L1CAM anticorps

Épitope: pSer1181

Fonction: Rabbit Anti-NCAM-L1 (phospho Ser1181) Polyclonal Antibody

Specificité: Phospho-NCAM-L1 (S1181) Polyclonal Antibody detects endogenous levels of NCAM-L1 protein only when phosphorylated at S1181.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human NCAM-L1 Phospho-Ser1181

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: NCAM-L1

Sujet: L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CD antigen CD171The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of L1CAM results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Poids moléculaire: 180kD

ID gène: 3897

UniProt: P32004

Pathways: Synaptic Membrane