LGALS12 anticorps (pSer736)
Aperçu rapide pour LGALS12 anticorps (pSer736) (ABIN7219010)
Antigène
Voir toutes LGALS12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer736
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Fonction
- Rabbit Anti-GRIP-1 (phospho Ser736) Polyclonal Antibody
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Specificité
- Phospho-GRIP-1 (S736) Polyclonal Antibody detects endogenous levels of GRIP-1 protein only when phosphorylated at S736.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human GRIP-1 Phospho-Ser736
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- LGALS12 (Lectin, Galactoside-Binding, Soluble, 12 (LGALS12))
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Autre désignation
- GRIP-1
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Sujet
- Glutamate receptor interacting protein 1, glutamate receptor-interacting protein 1, GRIP, GRIP-1Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).
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Poids moléculaire
- 180kD
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ID gène
- 10499
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UniProt
- Q15596
Antigène
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