LINGO1 anticorps (AA 370-450)

N° du produit ABIN7229400

Cet anticorps anti-LINGO1 Polyclonal Lapin (ABIN7229400) détecte spécifiquement LINGO1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour LINGO1 anticorps (AA 370-450) (ABIN7229400)

Antigène: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LINGO1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-LINGO1 anticorps

Épitope: AA 370-450

Fonction: Rabbit Anti-LIGO1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of LIGO1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human LIGO1 protein at AA range: 370-450

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LINGO1

Antigène: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Autre désignation: LIGO1

Sujet: Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6ALINGO1 (Leucine Rich Repeat And Ig Domain Containing 1) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. GO annotations related to this gene include epidermal growth factor receptor binding. An important paralog of this gene is LINGO2. Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed: 14966521, PubMed: 15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed: 15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Poids moléculaire: 68kD

ID gène: 84894

UniProt: Q96FE5