LECT1 anticorps (AA 150-230)

N° du produit ABIN7229384

L’anticorps anti-LECT1 Polyclonal Lapin est utilisé pour la détection de LECT1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour LECT1 anticorps (AA 150-230) (ABIN7229384)

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LECT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-LECT1 anticorps

Épitope: AA 150-230

Fonction: Rabbit Anti-LECT1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of LECT1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human LECT1 protein at AA range: 150-230

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LECT1

Antigène: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Autre désignation: LECT1

Sujet: Leukocyte cell-derived chemotaxin 1, ChondromodulinCNMD encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. CNMD is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 36kD

ID gène: 11061

UniProt: O75829