LIM Domain Binding 3 Protein anticorps (AA 41-90)

N° du produit ABIN7229370

Cet anticorps Lapin Polyclonal détecte spécifiquement LIM Domain Binding 3 Protein dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour LIM Domain Binding 3 Protein anticorps (AA 41-90) (ABIN7229370)

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Binding 3 Protein est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-LIM Domain Binding 3 Protein anticorps

Épitope: AA 41-90

Fonction: Rabbit Anti-LDB3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of LDB3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human LDB3 protein at AA range: 41-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LIM Domain Binding 3 Protein

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Autre désignation: LDB3

Sujet: LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif proteinLDB3 encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by LDB3 interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in LDB3 have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

Poids moléculaire: 79kD

ID gène: 11155

UniProt: O75112