LRP1B anticorps (AA 200-280)

N° du produit ABIN7229444

Cet anticorps Lapin Polyclonal détecte spécifiquement LRP1B dans IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour LRP1B anticorps (AA 200-280) (ABIN7229444)

Antigène: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP1B est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-LRP1B anticorps

Épitope: AA 200-280

Fonction: Rabbit Anti-LRP1B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of LRP1B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human LRP1B protein at AA range: 200-280

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur LRP1B

Antigène: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Autre désignation: LRP1B

Sujet: Low-density lipoprotein receptor-related protein 1B, LRP-1B, Low-density lipoprotein receptor-related protein-deleted in tumor, LRP-DITLRP1B is a putative tumor suppressor and a member of the low-density lipoprotein (LDL) receptor family. The LDL receptor family have roles related to clearance of extracellular ligand and are proposed to be involved in extracellular signal transduction. silencing and down-expression of LRP1B as been observed in renal cell carcinoma and thyroid cancer. Further Deletion of LRP1B has been associated with chemotherapy resistance in high-grade serous cancers.

Poids moléculaire: 505kD

ID gène: 53353

UniProt: Q9NZR2