MDH1 anticorps
Aperçu rapide pour MDH1 anticorps (ABIN7229614)
Antigène
Voir toutes MDH1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- MDHC Polyclonal Antibody
-
Specificité
- The antibody detects endogenous levels of MDHC protein
-
Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
Immunogène
- Synthesized peptide derived from part region of human MDHC protein
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))
-
Autre désignation
- MDHC
-
Sujet
- Rabbit Anti-MDHC Polyclonal Antibody,Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase,MDH1 encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.,MDHC
-
Poids moléculaire
- observerd band 36kDa
-
ID gène
- 4190
-
UniProt
- P40925
Antigène
-