MRGPRX1 anticorps (AA 240-320)

N° du produit ABIN7220926

Cet anticorps Lapin Polyclonal détecte spécifiquement MRGPRX1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MRGPRX1 anticorps (AA 240-320) (ABIN7220926)

Antigène: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MRGPRX1 anticorps

Épitope: AA 240-320

Fonction: Rabbit Anti-MRGX1 Polyclonal Antibody

Specificité: MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human MRGX1 at AA range: 240-320

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MRGPRX1

Antigène: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Autre désignation: MRGX1

Sujet: MRGPRX1, MRGX1, SNSR3, SNSR4, Mas-related G-protein coupled receptor member X1, Sensory neuron-specific G-protein coupled receptor 3/4MRGPRX1 (MAS Related GPR Family Member X1) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. rphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed: 26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

Poids moléculaire: 36kD

ID gène: 259249

UniProt: Q96LB2