MMP17 anticorps (Cleaved-Gln129)

N° du produit ABIN7212492

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP17 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MMP17 anticorps (Cleaved-Gln129) (ABIN7212492)

Antigène: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP17 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MMP17 anticorps

Épitope: AA 80-160, Cleaved-Gln129

Fonction: Cleaved-MMP-17 (Q129) Polyclonal Antibody

Specificité: Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human MMP-17 at AA range: 80-160

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MMP17

Antigène: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Autre désignation: MMP-17

Sujet: Rabbit Anti-Cleaved-MMP-17 (Q129) Polyclonal Antibody,MMP17, MT4MMP, Matrix metalloproteinase-17, MMP-17, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP,MMP17 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. Matrix metallopeptidase 17 is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of matrix metallopeptidase 17 protein has been observed in osteoarthritis and multiple human cancers.,Matrix metalloproteinase-17

Poids moléculaire: observerd band 53kDa

ID gène: 4326

UniProt: Q9ULZ9