MED24 anticorps (AA 770-850)

N° du produit ABIN7217378

Cet anticorps anti-MED24 Polyclonal Lapin (ABIN7217378) détecte spécifiquement MED24 dans ELISA, WB, IF et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MED24 anticorps (AA 770-850) (ABIN7217378)

Antigène: MED24 (Mediator Complex Subunit 24 (MED24))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED24 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-MED24 anticorps

Épitope: AA 770-850

Fonction: Rabbit Anti-TRAP100 Polyclonal Antibody

Specificité: TRAP100 Polyclonal Antibody detects endogenous levels of TRAP100 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human TRAP100 at AA range: 770-850

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MED24

Antigène: MED24 (Mediator Complex Subunit 24 (MED24))

Autre désignation: TRAP100

Sujet: MED24, ARC100, CRSP4, DRIP100, KIAA0130, THRAP4, TRAP100, Mediator of RNA polymerase II transcription subunit 24, Activator-recruited cofactor 100 kDa component, ARC100, Cofactor required for Sp1 transcriptional activation subunit 4, CRSP cMED24 encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 110kD

ID gène: 9862

UniProt: O75448

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity