MED27 anticorps (AA 90-170)
Aperçu rapide pour MED27 anticorps (AA 90-170) (ABIN7225992)
Antigène
Voir toutes MED27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 90-170
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Fonction
- CRSP34 Polyclonal Antibody
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Specificité
- CRSP34 Polyclonal Antibody detects endogenous levels of CRSP34 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human CRSP34 at AA range: 90-170
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MED27 (Mediator Complex Subunit 27 (MED27))
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Autre désignation
- CRSP34
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Sujet
- Rabbit Anti-CRSP34 Polyclonal Antibody,MED27, CRSP34, CRSP8, Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8, CRSP complex subunit 8, Mediator complex subunit 27, P37 TRAP/SMCC/PC2 subunit, Transcriptional co,The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED27 (mediator complex subunit 27) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for MED27, and a pseudogene of MED27 is located on the long arm of chromosome 5.,Mediator of RNA polymerase II transcription subunit 27
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Poids moléculaire
- observerd band 35kDa
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ID gène
- 9442
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UniProt
- Q6P2C8
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Pathways
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Antigène
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